Antibacterial Activity and Phytochemical Constituents of Cinnamomum verum and Matricaria chamomilla from Sudan

Abstract

Author(s): Rania Mohamed Abdalla* and Abdelgadir Elfadil Abdelgadir**

The present study describes the phytochemical profile and antibacterial activity of the bark of Cinnamomum verum and flowers of Matricaria chamomilla profusely prescribed in traditional medicine in Sudan. Our phytochemical investigations revealed many principles of bioactive properties in animal and human, such as sterols, triterpens, flavonoids, tannins and alkaloids for Cinnamomum verum, sterols, triterpens, flavonoids, saponins, tannins and alkaloids for Matricaria chamomilla. The antibacterial activity was examined using agar well-diffusion method, using different extracts; Petroleum ether, ethyl acetate, methanol and ethanol against two gram positives (Staphylococcus aureus ATCC 25923, Bacillus subtilis NCTC 8236) and two gram negatives (Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853), the results showed that most extracts have significant antibacterial activity. The current study supports the employment of these plants in the Sudanese folk medicine and recommends further microbiological and pharmacological studies as a promising sources for new antibacterial agents.

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